It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease. Duragesic fentanyl transdermal dosing, indications. Touch the sticky side of the duragesic patch as little as possible see figure g. Duragesic is a skin patch containing fentanyl, an opioid pain medication. The patches are used to treat moderate to severe chronic pain in opioidtolerant patients, severe enough to require daily, aroundtheclock, longterm opioid treatment duragesic patches are used when other pain. Withdrawal symptoms, drug interactions, dosage, and pregnancy and breastfeeding safety are provided. Highdose fentanyl patch for cancer pain of a patient with. Jan 06, 2017 each fentanyl transdermal system is sealed in its own protective pouch. Duragesic fentanyl transdermal system cii pain patch. Duragesic label page 1 full prescribing information for use. Durogesic dtrans doses should be individualised based upon the status of the patient and should be assessed at regular intervals after application. Duragesic is a prescription medicine used as a transdermal patch to treat the. A strong prescription pain medicine that contains an opioid narcotic that is used to manage pain severe enough to require daily.
Pain home generic duragesic several companies manufacture a generic duragesic fentanyl patch product, including actavis u. Management of pain in opioidtolerant patients, severe enough to require daily, aroundtheclock, longterm analgesia for which alternative opioid therapies are inadequate. Side effects of duragesic fentanyl transdermal, warnings, uses. Fentanyl duragesic is a moderately priced drug used to treat chronic pain. Use duragesic fentanyl transdermal patch as ordered by your doctor. Patients who are opioid tolerant are those receiving, for 1 week or longer, at least 60 mgday morphine, 25 mcgday transdermal fentanyl, 30 mgday po oxycodone, 8 mgday po hydromorphone, 25 mgday po oxymorphone, 60 mgday po hydrocodone, or an equianalgesic dose of another opioid. Side effects may include profuse sweating, coughing, nausea, diarrhea, and tearing.
Eligible patients using commercial or private insurance can save on outofpocket costs for duragesic. The entire stock of pricaras fentanyl transdermal system cii patches are a part of the recall. The duragesic fentanyl patch provides longterm pain relief and lowers the number of times you need to take pain medications each day. Opioid analgesic, anesthesia adjunct controlled substance schedule ii pregnancy risk category c action binds to specific opioid. Using damaged or cut duragesic patches can lead to the rapid release of the contents of the.
Side effects of duragesic fentanyl transdermal, warnings. Many drugs interact with fentanyl transdermal patch and can raise the chance of side effects like deadly breathing problems. Dec 23, 2019 duragesic is the brand name of fentanyl transdermal therapeutic systems which is a system of delivering pain relief in the form of a patch placed on the skin. The patches are designed to deliver approximately 12, 25, 50, 75, and 100 mcgh fentanyl to the systemic circulation, which represent about 0. See the section below disposing ofa duragesic patch. Jill green is a 42yearold mother of two who has been married for 17 years. Fentanyl patches may be habit forming, especially with prolonged use. Do not apply more patches, apply the patches more often, or use the patches in a different way than prescribed by your doctor. Durogesic dtrans 12 mcghr transdermal patch summary of. Do not take with alcohol or products that have alcohol. The transdermal patch is a longacting formulation with a delayed onset of effect initially and a prolonged duration of action.
Duragesic fentanyl transdermal dosing, indications, interactions. The next patch is applied to a different skin site after removal of the previous transdermal system. Eat a well balanced diet high in bcomplex vitamins. Rotate patch sites with every change every 72 hours. Fentanyl transdermal patch 72 hour 100mcg drug medication dosage information. Fentanyl dose conversion guidelines current analgesic daily dosage mgd oral morphine 604 5224 225314 315404 imiv morphine 10 to 22 2337 3852 5367. The patch should be applied to a clean, dry area on the upper arm or back. Duragesic fentanyl transdermal drugs requiring prior authorization drugs requiring prior authorization label name gcn duragesic 12 mcghr patch 24635 duragesic 25 mcghr patch 19200 duragesic 50 mcghr patch 19201 duragesic 75 mcghr patch 19202 duragesic 100 mcghr patch 19203 fentanyl 12 mcghr patch 24635. Duragesic patches are intended for transdermal use on intact skin only. Fentanyl belongs to a general class of drugs known as opiates or. Instructions for use duragesic instructions for applying a. Fentanyl is also used as a recreational drug, often mixed with heroin or cocaine. Do not apply to an area that has hair unless hair is shaved d.
Fentanyl patch protocol ventura county, california. Duragesic fentanyl dose, indications, adverse effects. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. For the last 2 years she has undergone intensive chemotherapy and radiation. Fentanyl, also spelled fentanil, is an opioid used as a pain medication and together with other medications for anesthesia. Do not apply the new patch to the same place as the last one. Fentanyl transdermal patch duragesic is a prescription medication used to treat severe chronic pain such as cancer. Each duragesic patch may be worn continuously for 72 hours. The highest dose of transdermal fentanyl reported in the english medical literature was 3,400 ghr 34 patches of 100 ghr each, which used. Duragesic fentanyl transdermal indications and dosage. Duragesic fentanyl is stronger than morphine, works quickly, and doesnt cause as many stomach problems.
Peel off both parts of the release liner from the patch. Medscape analgesic dosing for duragesic fentanyl transdermal. Fentanyl patches may cause serious or lifethreatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is. The amount of fentanyl in a new or used patch could be fatal to a child or pet who accidentally chews, sucks on, or swallows the patch. Fentanyl also can cause sedation and depression of the central nervous system. The following conditions are contraindicated with this drug. Duragesic is a longacting extendedrelease opioid pain medicine narcotic that can put you at risk for overdose and death.
Remove a duragesic patch after wearing it for 3 days 72 hours. Duragesic fentanyl transdermal system for transdermal administration is an opioid analgesic indicated for the management of pain in opioidtolerant patients, severe enough to require daily, aroundtheclock, longterm opioid treatment and for which alternative treatment options are inadequate. Fentanyl is gradually absorbed from a transdermal patch placed on the skin and produces analgesic effects lasting from 48 to 72 hours. The contents of durogesic patches may be retrieved and potentially abused. Its available in many dosage forms, including a patch, injection, film, nasal spray, and lollipop.
Fold used patches so that the adhesive side of the patch adheres to itself then wrap and dispose of carefully. Highdose fentanyl patch for cancer pain pubmed ncbi nih. Fentanyl transdermal system fentanyl transdermal system for. Oral morphine is preferred because of the relative ease of dose adjustments. Duragesic fentanyl transdermal system for transdermal administration, cii. Remove the old patch before applying the new patch c. Each duragesic patch has a clear plastic release liner that can be peeled off in two pieces. Aug 12, 2019 durogesic dtrans doses should be individualised based upon the status of the patient and should be assessed at regular intervals after application. Fentanyl is available as an injectable solution or as a transdermal skin patch. Fentanyl transdermal patch 72 hour 100mcg drug medication. Duragesic fentanyl transdermal system is available in generic form.
Serious or lifethreatening breathing problems that can lead to death can. Follow the information that comes with fentanyl transdermal patch for throwing out doses that are not needed. Duragesic definition of duragesic by medical dictionary. It has a rapid onset and its effects generally last less than two hours. Jul 18, 2015 fentanyl, also known as duragesic and sublimaze, is a very potent medication used to control pain for dogs and cats. After the initial diagnosis jill had a total hysterectomy with salpingooophorectomy. Dec 22, 2019 store fentanyl transdermal patch in a safe place where children cannot see or reach it, and where other people cannot get to it. If necessary, clip hair from the site prior to applying the patch. Fentanyl transdermal system duragesic 12 mcghr25 mcghr375. Do not remove a fentanyl transdermal system from the pouch until you are ready to use it. Talk with your doctor and pharmacist to make sure it is safe to use fentanyl transdermal patch with all of your drugs. Remove the patch from the package, peel off the protective strip and immediately apply it to the site.
The content on this site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Fentanyl patch protocol please use the following chart to determine whether or not the prescribed fentanyl dose is appropriate for your patient. Using damaged or cut duragesic patches can lead to the rapid release of the contents of the duragesic patch and absorption of a potentially fatal dose of fentanyl. Fentanyl accumulates to form a depot in the skin below the. Read the medication guide and, if available, the instructions for use provided by your pharmacist before you start using. Do not use a fentanyl transdermal system if the pouch seal is broken or the patch is cut, damaged or changed in any way. Mylan manufactures fentanyl transdermal system duragesic in strengths of 12 mcghr25 mcghr375 mcghr50 mcghr625 mcghr75 mcghr875 mcghr100 mcghr. Fentanyl patches durogesic for chronic pain nps medicinewise. Nonparenteral fentanyl products are contraindicated for use in patients with acute or severe bronchial asthma e. Durogesic patch is packed in a heatsealed pouch and is supplied in cartons containing 5 pouches. Press firmly for 30 seconds to make sure the patch stays in place. Although the approved indication and the pbs listing allow use of the fentanyl patch. If problems with adhesion of the duragesic patch occur, the edges of the patch may be taped with first aid tape.
Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to overdose or death. Duragesic patch fentanyl patch rationale for inclusion in pa. Concomitant use of fentanyl injection with cyp3a4 inducers or discontinuation of a cyp3a4 inhibitor could decrease fentanyl plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to fentanyl. Throughout america duragesicfentanyl patches are being. Duragesic patch and absorption of a potentially fatal dose. Medically, fentanyl is used by injection, as a patch on the skin. The patches are designed to deliver approximately 12, 25, 50, 75, and 100 mcgh fentanyl to the systemic circulation. Repeat steps 2 through 6above when applying a new duragesic patch. Choose a different skin site to apply a new duragesic patch. A locked box or area may help keep fentanyl transdermal patch safe. Generic fentanyl is covered by some medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Duragesic fentanyl transdermal system is supplied in cartons containing 5 individually packaged systems. The duragesic transdermal system patch is used for the management of persistent, moderate to severe chronic pain in opioidtolerant patients when a continuous, aroundtheclock opioid analgesic is needed for an extended period of time. Duragesic patches are a strong prescription pain medicine. Carefully peel this release liner off and throw the pieces away. The united states food and drug administration has determined that the generic versions of duragesic are equivalent to the brandname drug. See chart for information regarding individual systems.667 604 156 20 64 507 1004 1449 508 1411 1304 1504 768 538 9 915 1006 459 1299 942 240 1143 343 863 1248 670 808 401 836 1031 813 640 129 894 400 598 1182